MUSYC – Brain surgery and delirium in adults

MusiC to prevent deliriUm during neuroSurgerY

Pablo Kappen

Pablo now has approval of the protocol from the Medical Ethics Committee, so he can start the research. By the end of 2021, he hopes to have enough patients.


Examining the effect of music in preventing the development of delirium after brain surgery.

Delirium is a psychotic psychiatric disease with acute onset. It is a common and severe side effect after brain surgery. Effective treatments for the prevention of delirium are not available.

Delirium is induced by stress and anxiety, particularly in patients with an affected brain. Music has proven to decrease stress and anxiety around surgical procedures. We therefore believe that music could lower the chance of developing delirium after brain surgery.

Decreasing delirium might shorten the length of stay in the hospital, the chance of developing other admission related side effects and this might improve the patients’ outcome in the long-term.

Project Funding

This research has already been fully funded.

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Presentation by Pablo Kappen

An underestimated complication

Delirium occurs in 30% of cases after brain surgery. Delirium is a state of acute confusion with hallucinations and is an unpleasant experience for patient and family.